A recent article published in September of 2020 by The Spine Journal features a pilot study that gives great hope to patients suffering from spinal pain. The patients included in the study were diagnosed with HNP (herniated nucleus pulposus), DDD (degenerative disc disease) or spinal stenosis. Their lower back pain and leg pain had persisted for over 3 months, and all selected patients had tried medication, gone through physical therapy and chiropractic therapy without relief. The patients were divided into 3 groups based on their diagnosis (HNP, DDD, spinal stenosis) and received 2mL of epidural amniotic fluid at a symptomatic spinal level using fluoroscopy. The outcomes were measured at 2 weeks, 6 weeks, 3-4months, 6 months and 1 year.

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No adverse effects or complications were reported. Patients in all groups reported decrease in symptoms, with AF epidural injections for lumbar HNP having the most effectiveness. These patient outcomes were measured by the visual-analog scale for back and leg pain, pain diagrams, Odswestry Disability Index and Patient Reported Outcomes Measurement Information System-Phys. This study paves the way for greater large-scale comparative studies and suggests that amniotic fluid injections can provide pain relief due to it’s components that are rich in anti-inflammatory agents.

Source: Glenn R. Buttermann, Louis C. Saeger, Matthew G. Thorson, 166. Effectiveness of epidural amniotic fluid injection for low back pain, The Spine Journal, Volume 20, Issue 9, Supplement, 2020, Page S82, https://doi.org/10.1016/j.spinee.2020.05.577. https://www.thespinejournalonline.com/article/S1529-9430(20)30842-1/pdf